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Monday, April 27, 2009

PIRACETAM, OTC drug



  • Piracetam ; i looked into this drug and tried it out, it did increase all of the stated benefits, so i thought i would share. Google the name for personal research and companies that sell by mail.* Piracetam (brand name: Nootropil, Qropi, Myocalm, Dinagen, Synaptine) is a nootropic. It is a dietary supplement which is claimed to enhance
  • cognition and memory, slow down brain aging, increase blood flow and oxygen to the brain, aid stroke recovery, and improve Alzheimer's, Down syndrome, dementia, and dyslexia, among others._ _Piracetam's chemical name is 2-oxo-1-pyrrolidine acetamide; it shares the same 2-oxo-pyrrolidone base structure with 2-oxo-pyrrolidine carboxylic acid (pyroglutamate). Piracetam is a cyclic derivative of GABA. It is one of the racetams. Piracetam is prescribed by doctors for some conditions, mainly myoclonus,but is used off-label for a much wider range of applications. However, some treat it as a food supplement rather than a drug Piracetam (brand name: Nootropil, Qropi, Myocalm, Dinagen, Synaptine) is a nootropic. It is a dietary supplement which is claimed to enhance cognition and memory, slow down brain aging, increase blood flow and oxygen to the brain, aid stroke recovery, and improve Alzheimer's, Down syndrome, dementia, and dyslexia, among others.Piracetam's chemical name is 2-oxo-1-pyrrolidine acetamide; it shares the same 2-oxo-pyrrolidone base structure with 2-oxo-pyrrolidine carboxylic acid (pyroglutamate). Piracetam is a cyclic derivative of GABA. It is one of the racetams. Piracetam is prescribed by doctors for some conditions, mainly myoclonus,but is used off-label for a much wider range of applications. However, some treat it as a food supplement rather than a drug Piracetam was first synthesized in 1964 by scientists at the Belgian pharmaceutical company UCB led by Dr Corneliu E. Giurgea. The drug was the first of the so-called +nootropics+ ("smart drugs" or "cognitive enhancers"), that is, substances which purportedly enhance mental performance. The term nootropic was coined by Giurgea. Nootropil was launched clinically by UCB in the early 1970s and remains an important product of that company in Europe. Piracetam is primarily used in Europe, Asia, South America and the US. Piracetam is legal to import into the United Kingdom and the United States for personal use with or without prescription. As of June 2006, piracetam is sold in the United States as a dietary supplement. It has become popular as a cognitive enhancement drug among students, who often buy it in bulk as a powder and then consume it with orange or grapefruit juice to mask the strong, bitter taste. A two week regimen of piracetam was found to enhance verbal memory in healthy college students in a double-blind, placebo-controlled study.It is used by parents as a treatment for childhood autism, though no study has yet produced results which would support such a use. A couple of vendors offering Piracetam in pill form in the USA include American Nutrition (AmericanNutrition.com) and Cognitive Nutrition (CognitiveNutrition.com). Aging Piracetam appears to reverse the effects of aging in the brains of mice. Piracetam appears to reduce levels of lipofuscin in the rat brain.(Lipofuscin accumulation is a common symptom of aging and alcoholism). Alcoholism Piracetam appears to be effective in treating alcoholism or its symptoms. Alzheimer's and senile dementia Piracetam appears to be effective for improving cognition in Alzheimer's disease and senile dementia patients Stroke, ischemia and symptoms Piracetam has been found to improve cognition after stroke, and reduce symptoms, such as aphasia.It also improves cognition in cases of chronic ischemia. Dyspraxia and Dysgraphia Due to its supposed effect on nerves and muscles it is sometimes prescribed as an aid to muscle or dexterity training, particularly in cases of dysgraphia and dyspraxia. There has not been a specific study as to whether it is beneficial in this aspect. Vinpocetine, another purported nootropic with which piracetam is indirectly synergesic, is confirmed to help with these conditions to a certain degree. Schizophrenia Piracetam improves cognitive performance of schizophrenics as it does with non-schizophrenics, but does not improve or worsen the chronic schizophrenia disease state. Brand names Nootropil, Qropi, Myocalm, Dinagen, Oikamid, Synaptine Due to the effect of piracetam on platelet aggregation, caution is recommended in patients with underlying disorders of hemostasis, major surgery or severe hemorrhage. Abrupt discontinuation of treatment should be avoided as this may induce myoclonic or generalised seizures in some myoclonic patients. As piracetam is almost exclusively excreted by the kidneys caution should be exercised in treating patients with known renal impairment. In renally impaired and elderly patients, an increase in terminal half-life is directly related to renal function as measured by creatinine clearance. Dosage adjustment is therefore required in those with mild to moderate renal impairment and elderly patients with diminished renal function.

    1 comment:

    Phrenism said...

    Piracetam is a great substance, definitely helped me in many ways. I wrote an article about it http://hubpages.com/hub/Piracetam-The-nootropic-Wonder-Drug